BDBM473172 (3R,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)-1,2-dithiolan-4-ol::US10844038, Example 46 B.
SMILES Nc1ncnc2n(C[C@H]3SSC[C@H]3O)nc(-c3ccc(Oc4ccccc4)cc3)c12
InChI Key InChIKey=UORAPQCBWYIISR-IAGOWNOFSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 473172
TargetDual specificity mitogen-activated protein kinase kinase 5(Homo sapiens (Human))
Sabila Biosciences
US Patent
Sabila Biosciences
US Patent
Affinity DataIC50: 5.50E+3nMAssay Description:IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ...More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 5(Homo sapiens (Human))
Sabila Biosciences
US Patent
Sabila Biosciences
US Patent
Affinity DataKd: <5nMAssay Description:Kd: For most assays, kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase an...More data for this Ligand-Target Pair